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Rotavac, a rotavirus vaccine produced by Hyderabad-based Bharat Biotech, became part of Indiaâs Universal Immunisation Programme (UIP) when it was introduced in 4 states in April 2016, and was subsequently extended to 5 more states last month. The key step forward in the manufacture of Serum Institute of Indiaâs new BRV-PV vaccine â to be ultimately called Rotasiil â is that it does not, unlike Rotavac, require refrigeration, and is, therefore, easier to store in low-income countries where rotavirus poses the greatest threat to children.