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GLIBEN 5 MG 100 TABLET is a combination of three antidiabetic medicines: Glibenclamide, Metformin and Rosiglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glibenclamide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide.